Characteristics
- INCI
- Phytosphingosine
- CAS
-
554-62-1
This is the substance number in the Chemical Abstracts Service registry. The CAS number uniquely identifies a substance regardless of language, trade name, or synonyms.
- IUPAC
- 1,3,4-Octadecanetriol, 2-Amino-, (2S, 3S, 4R)-
- Functions
- hair conditioning, skin conditioning
Who it's for
Description
If your skin had a backstage crew, Phytosphingosine would be one of the quiet workers keeping everything running smoothly. It’s a naturally occurring skin lipid, a sphingoid base found in the outer layers of your skin, where it helps make up part of the barrier that keeps water in and irritants out. It also shows up as a building block of ceramides, so yes, it hangs out in some very important skin-company.
What makes it interesting is that it seems to do more than just sit there looking biochemically elegant. Research suggests phytosphingosine has cell-communicating and antimicrobial properties, which means it may help skin defend itself and behave a little more sensibly under stress. That’s why it’s often discussed as part of the skin’s own defense system rather than just a random added lipid. In other words, it looks like something your skin already knows and likes.
It has also gotten attention for acne-prone skin. A 2007 study found that phytosphingosine showed activity against Cutibacterium acnes (formerly known as Propionibacterium acnes), the bacterium involved in acne, and it also appeared to have anti-inflammatory effects. That makes it a promising helper in formulas aimed at blemish-prone or easily irritated skin, especially when the goal is to support the barrier without piling on harsher ingredients. It’s not a dramatic overnight fix, but it can be a smart supporting act.
So if you spot phytosphingosine on an ingredient list, that’s usually a good sign your formula is trying to be a bit more skin-friendly and barrier-minded. It’s one of those nerdy-but-useful ingredients that doesn’t get much attention at parties, yet your skin may very much appreciate having around.
More detail
It's a type of lipid, a so-called sphingoid base that can be found naturally in the upper layer of the skin. It's found both in "free-form" and as part of famous skin lipids, ceramides.
There is emerging research about Phytosphingosine that shows that it has antimicrobial and cell-communicating properties and is considered part of the skin's natural defense system.
A 2007 study showed that Phytosphingosine even works against evil acne-causing bacteria, Propionibacterium acnes and shows promise as a complementing active ingredient in treating acne-prone skin thanks to its anti-inflammatory and antimicrobial activities.
A nice one to spot in the ingredient list. :)
Evidence & Research on Phytosphingosine
-
1
International Journal of Cosmetic Science, June 2007, Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris
Products with Phytosphingosine (3 666 total)
Most often found in CeraVe products (155 items)